Heat-Shock Protein 27 (HSPB1) Is Upregulated and Phosphorylated in Human Platelets during ST-Elevation Myocardial Infarction
نویسندگان
چکیده
منابع مشابه
The Clinical Significance of Phosphorylated Heat Shock Protein 27 (HSPB1) in Pancreatic Cancer
Pancreatic cancer is one of most aggressive forms of cancer. After clinical detection it exhibits fast metastatic growth. Heat shock protein 27 (HSP27; HSPB1) has been characterized as a molecular chaperone which modifies the structures and functions of other proteins in cells when they are exposed to various stresses, such as chemotherapy. While the administration of gemcitabine, an anti-tumor...
متن کاملST-Elevation Myocardial Infarction
Background—In the United States, efforts are underway to improve timely access to percutaneous coronary intervention in ST-elevation myocardial infarction (STEMI). The Joint Commission (TJC) and the American College of Cardiology National Cardiovascular Data Registry (NCDR) have developed standardized definitions and clinical performance measures for STEMI. The purpose of this study was to dete...
متن کاملHeat Shock Protein 27 Is Spatially Distributed in the Human Placenta and Decreased during Labor
Placental oxidative stress is a feature of human labor. Heat shock proteins (HSPs) play a key role in cellular stress. We hypothesized that placental expression of the small HSP 27 would be altered during labor and expression would vary in different regions of the placenta. Six women in labor who delivered vaginally and 6 women not in labor, who were delivered by Cesarean section, were recruite...
متن کاملMistaken ST-Elevation Myocardial Infarction.
A 66-year-old female was transferred from an outside hospital for possible ST segment elevation myocardial infarction (STEMI). The patient reported feeling poorly for the last day, with epigastric pain, nausea, and multiple episodes of vomiting. Patient’s medical history was significant for diabetes mellitus, hypertension, atrial fibrillation, and multiple sclerosis. Electrocardiogram (EKG) was...
متن کاملHeat-shock protein 27 is phosphorylated in gemcitabine-resistant pancreatic cancer cells.
BACKGROUND Gemcitabine (2'-deoxy-2'-difluorodeoxycytidine: Gemzar) (GEM) appears to be the only effective anticancer drug for pancreatic cancer, but it has little impact on outcome due to a high level of inherent and acquired tumor resistance. Our previous proteomic study demonstrated that the expression of three spots of heat-shock protein 27 (HSP27) was increased in GEM-resistant pancreatic c...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20235968